Mycotoxin Cleaning Checklist: A Step-by-Step Guide from an Indoor Environmental Professional

If you’ve experienced mold contamination in your home, you may be wondering how to fully clean your environment—even after the visible mold is gone. Mycotoxins, the toxic byproducts released by certain mold species, can linger on surfaces, in fabrics, and in household dust long after remediation. These toxins can contribute to chronic health issues, especially for those with mold sensitivities or immune system vulnerabilities.

As indoor environmental professionals, we often assist clients in addressing lingering mycotoxin concerns after mold removal. Below is a comprehensive mycotoxin cleaning checklist designed to support a cleaner, safer indoor environment.


Mycotoxin Cleaning Checklist

1. Assessment and Validation

  • Identify prior or active mold growth areas within the home.
  • Have the environment reviewed by a Certified Indoor Environmental Professional (IEP).
  • Use findings from the IEP to prioritize treatment zones—especially living areas, bedrooms, HVAC systems, and soft goods like furniture and bedding.

2. Clean All Surfaces and Contents

Hard Surfaces

  • Begin with a general cleaning using soap and water.
  • Follow with a non-toxic antimicrobial cleaner to target residual contamination.
  • Focus on walls, floors, baseboards, furniture surfaces, shelving, and electronics.

Porous and Semi-Porous Surfaces

  • Use a certified HEPA vacuum to clean upholstery, carpets, curtains, and mattresses.
  • Wash removable fabrics in hot water with mold-safe laundry additives or odor-neutralizing agents.
  • Items heavily contaminated or emitting musty odors may need to be discarded, especially if the IEP recommends removal.

3. Fogging or Misting for Mycotoxin Neutralization

  • After surface cleaning, consider using a cold fogging or electrostatic spraying method to reach airborne particles and hard-to-access areas.
  • Fogging helps bind and neutralize residual spores and mycotoxins that may still be present.
  • Be sure to fog with HVAC systems turned off, and allow for adequate ventilation afterward.

4. Air Treatment and Environmental Control

  • Run a HEPA-certified air purifier or scrubber to help remove airborne mold spores and mycotoxin-laden dust.
  • Place natural toxin adsorbers in areas with porous materials to help reduce residual contamination.
  • Consider using a hydroxyl generator to assist in the breakdown of airborne volatile organic compounds (VOCs) and some types of mold-related toxins.

5. Binding Agents for Environmental Support

  • Use natural absorbents such as activated charcoal, zeolite, or clay-based materials in drawers, closets, and near soft furniture to help bind toxins.
  • These materials may help reduce the re-circulation of mycotoxins into the breathing zone and are often recommended in sensitive environments.

6. Ongoing Maintenance for Long-Term Air Quality

  • Maintain indoor humidity below 50% using a dehumidifier or HVAC adjustments.
  • Vacuum and dust regularly using HEPA-grade equipment to remove mold spores and dust-bound toxins.
  • Clean air vents and change HVAC filters regularly (MERV 11–13 recommended).
  • Consider periodic fogging or professional air quality evaluations if symptoms persist or if the building has a history of water damage.
  • Monitor indoor air quality with consumer-grade VOC and particulate meters.

Why This Matters

Mycotoxin contamination can be persistent, especially in porous materials and indoor dust. Cleaning without professional guidance often fails to address the full picture, leading to ongoing exposure and recurring symptoms. Working with an indoor environmental professional can help ensure that every step—from identification to final clearance—is handled with care and expertise.


Final Thoughts

Addressing mold and mycotoxins requires a holistic approach: identifying the source, removing contamination, improving air quality, and preventing recurrence. Whether you’re recovering from a recent mold remediation or suspect hidden contamination, this mycotoxin cleaning checklist can guide you toward a healthier indoor space.